Hi, I'm Leo Joseph

Passionate about applying machine learning to solve complex biological problems. Currently developing computational tools for microbiome studies at Knight Lab, UCSD.

When I'm not a student, I like to drink coffee, take photos, and pursue athletic endeavors.

Leo Joseph at half marathon
Featured Projects

Check out my work

Here are some of the projects I've worked on during my time at UCSD.

Qupid - Microbiome Analysis Tool

A software tool for case-control matching in microbiome studies.

Scikit-BioQIIME 2Jupyter Notebooks
View Project

KnightGPT

A microbiome specific Graph-Retrieval Augmented Generation system that enhances language models.

Large Language ModelsGraph-RAGOllama
View Project

HRD Detection Algorithm

Machine learning algorithm to detect Homologous Recombination Deficiency from RNA-seq data of breast and ovarian cancer data.

Machine LearningRNA-seqCancer BiologyR
View Project

IDEA (Interactive Differential Expression Analysis)

Python package designed for performing differential expression analysis on gene expression data. (Designed as a Python equivalent to DESeq2)

Python packaging & distributionDESEQ2R
View Project

Skywalker V2 Prosthetic Arm

A low-cost prosthetic arm with EMG signal processing and machine learning-driven motion control.

Additive ManufacturingPyTorchArduino
View Project
My Skills

Technologies I work with

I'm proficient in a variety of programming languages and tools used in bioinformatics and software development.

Programming Languages

PythonRJavaC++

Machine Learning

TensorFlow/KerasPyTorchscikit-learn

Web Technologies

HTML/CSSJavaScriptReactFlaskDjangoD3.js

Bioinformatics Tools

BIRDMAnQuitaQiime2BLASTHMMERBiopythonSamtools

Cloud Platforms

AWSAzure

Version Control

GitGitHub
About Me

Educational & Professional Background

I'm a bioinformatics-focused developer currently studying at the University of California, San Diego (UCSD). I'm pursuing a Bachelor's degree in Bioengineering: Bioinformatics, expected to graduate in June 2025.

My experience spans from academic research to industry internships. At the Knight Lab at UCSD, I've been working on microbiome studies. I primarily focus on Autism Spectrum Disorder (ASD), using advanced machine learning and bioinformatics techniques to identify and diagnose ASD using the gut microbiome.

Education

University of California, San Diego

Bachelor of Science in Bioengineering: Bioinformatics

Expected Graduation: June 2025

Relevant Experience

  • Knight Lab - UCSD (Dec 2023 - Present)
  • Kaiser Permanente Intern (Jun 2023 - Sep 2023)
  • Clear Labs R&D Intern (Jun 2021 - Aug 2021)
  • Cisco Software Engineer Intern (Jun 2021 - Aug 2021)

Relevant Coursework

  • Design & Analysis of Algorithms
  • Applied Genomic Technologies
  • Advanced Bioinformatics Lab
  • Supervised Machine Learning Algorithms